コメダ　ヒデツグ   KOMEDA Hidetsugu   米田　英嗣    所属   青山学院大学  教育人間科学部 教育学科    職種   教授
言語種別	英語
発行・発表の年月	2023/08
形態種別	学術雑誌
査読	査読あり
標題	Measurements of the lateral cerebellar hemispheres using near-infrared spectroscopy through comparison between autism spectrum disorder and typical development.
執筆形態	共同
掲載誌名	Neuroscience letters
掲載区分	国外
巻・号・頁	812,pp.137381
著者・共著者	Toshiki Nishida, Nao Suzumura, Yuto Nakanishi, Nao Maki, Hidetsugu Komeda, Masahiro Kawasaki, Yasuko Funabiki
概要	The cerebellum plays a vital role in cognition, communication with the cerebral cortex, and fine motor coordination. Near-infrared spectroscopy (NIRS) is a portable, less restrictive, and noninvasive functional brain imaging method that can capture brain activity during movements by measuring the relative oxyhemoglobin (oxy-Hb) concentrations in the blood. However, the feasibility of using NIRS to measure cerebellar activity requires discussion. We compared NIRS responses between areas assumed to be the cerebellum and the occipital lobe during a fine motor task (tying a bow knot) and a visual task. Our results showed that the oxy-Hb concentration increased more in the occipital lobe than in the cerebellum during the visual task (p =.034). In contrast, during the fine motor task, the oxy-Hb concentration decreased in the occipital lobe but increased significantly in the cerebellum, indicating a notable difference (p =.015). These findings suggest that we successfully captured cerebellar activity associated with processing, particularly fine motor coordination. Moreover, the observed responses did not differ between individuals with autism spectrum disorder and those with typical development. Our study demonstrates the meaningful utility of NIRS as a method for measuring cerebellar activity during movements.
DOI	10.1016/j.neulet.2023.137381
ISSN	1872-7972
PMID	37419305