スギムラ　ヒデユキ   SUGIMURA Hideyuki   杉村　秀幸    所属   青山学院大学  理工学部 化学・生命科学科    職種   教授
言語種別	英語
発行・発表の年月	2023/09
形態種別	学術雑誌
査読	査読あり
標題	Access to polysubstituted pyrimidine derivatives via the aza-Diels–Alder reaction of 1,2,3-triazine derivatives and amidines
執筆形態	共同
掲載誌名	Tetrahedron
掲載区分	国外
出版社・発行元	Elsevier
巻・号・頁	146,pp.133629
総ページ数	8
担当区分	筆頭著者
著者・共著者	Minami Usami, Asuka Matsuzawa, Akane Yamada, Ikuo Sasaki, Hideyuki Sugimura
概要	The synthesis of highly substituted pyrimidine derivatives by the aza-Diels–Alder reaction of 1,2,3-triazines with amidine derivatives is described. This reaction provided direct access to a wide range of 6-aryl-2-substituted pyrimidine-4-carboxylates in good yields with good functional group compatibility. A broad substrate scope, and the operationally simple, metal-free, and neutral reaction conditions are the prominent features of this method.